Research Article
Open Access
GC-MS Analysis of Methanolic Extract of Phyllanthus Amarus Leaves Collected From Salem Region
Saradhai Pandurangan1*, Arthi Mohan2, Balakrishnan Sethuramali1, Saravanan Ramalingam3
Saradhai Pandurangan1*, Arthi Mohan2, Balakrishnan Sethuramali1, Saravanan Ramalingam3
Saradhai Pandurangan, Arthi Mohan, Balakrishnan Sethuramali, Saravanan Ramalingam. GC-MS Analysis of Methanolic Extract of Phyllanthus amarus Leaves Collected From Salem Region. Asian Journal of Pharmacology and Toxicology, 03(10), 2015, 54-59.
Abstract
Leaves of Phyllanthus amarus are used traditionally by Indian and Chinese system of traditional medicine for the treatment of several diseases like hepato-renal, skin and other infectious diseases. Methanolic extract of P. amarus from Salem region was screened for the presence of several bioactive compounds. It was evaluated using GC-MS analysis. The methanolic extract revealed the presence of 17 medicinally important bioactive compounds among those 9,12,15- Octadecatrienoic acid (Z,Z,Z) – showed highest peak of 9.10%, followed by gamma tocopherol - 6.04 %, oxozalone - 3.59%, n-hexadecanoic acid - 2.59%, Octadecanoic acid - 1.92%, 9,17- Octadecadienal (Z) - 0.43% and Phytol - 0.61% identified during analysis.
Keywords
P. amarus, Hepato-renal, GC- MS, Bioactive compounds
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