Research Article
Open Access
Domperidone induced neuroleptic malignant syndrome: an uncommon toxicity of a common drug.
Upinder Kaur, Sankha Shubhra Chakrabarti, Indrajeet Singh Gambhir
Division of Geriatrics, Department of General Medicine Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, UP.
Upinder Kaur, Sankha Shubhra Chakrabarti, Indrajeet Singh Gambhir. Domperidone induced neuroleptic malignant syndrome: an uncommon toxicity of a common drug. Asian Journal of Pharmacology and Toxicology, 03(11), 2015, 22-24.
Abstract
Domperidone is commonly used as an antiemetic and prokinetic drug. Its safety profile is presumed to be good and serious side effects are seldom associated with it. The elderly population in general is more susceptible to adverse drug reactions owing to altered pharmacokinetics and pharmacodynamics. Here we present a case of neuroleptic malignant syndrome in an elderly lady who was prescribed domperidone.
Keywords
Neuroleptic malignant syndrome, domperidone, _ geriatric pharmacology, pharmacovigilance
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