Research Article
Open Access
Pharmacological investigation of leaf extract of Typha angustata for depressant activity
K. Ashok Kumar*, M. Sathish Kumar, A. Narendra Babu, D. Eswar tony, N.V. Rama Rao, G. Divya Sri, M. Dastagiri
Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Lam, Guntur.
K. Ashok Kumar, M. Sathish Kumar, A. Narendra Babu, D. Eswar tony, N.V. Rama Rao, G. Divya Sri, M. Dastagiri Pharmacological investigation of leaf extract of Typha angustata for depressant activity. Asian Journal of Pharmacology and Toxicology 02 (03); 2014; 01-03.
Abstract
The methanolic leaf extract of Typha angustata was intended to evaluate the effect on the central nervous system (CNS) using a number of neuro pharmacological experimental models like open field test, hole board apparatus in mice. The extract, at the dose of 100 mg/kg body weight was shown significant CNS depressant activity by reduction in rearing and number of squares crossed in open field and reduction in head dipping in hole board apparatus. These results suggest that the methanolic extract possess significant CNS depressant activity when compared to the other groups.
Keywords
Typha angustata, depressant activity, open field, hole board test.