Anuradha VivekanandPhatak

ABSTRACT

Aim of the study was to study effects of repeated dose administration of extract of roots of Spermadictyonsuaveolensin streptozotocin induced diabetic rats.Effects of extract of Spermadictyonsuaveolenswasstudied in streptozotocin-induced diabetic rats. 1 week after the administration of streptozotocin, diabetic rats received herbal extract orally at dose 500 mg/kg body weight for 28 consecutive days.Administration of streptozotocin resulted in 3-4 fold increase in fasting plasma glucose level. Treatment with herbal extract showed glucose lowering effect from first week. Results show that extract of roots of Spermadictyonsuaveolenspossesses antidiabetic activity.