Sunil Prashar

ABSTRACT

Background: Snake bite is an occupational hazard that leads to significant number of fatalities and medical emergencies in developing countries. The focus of research in the field of snake bite management is now on the plant kingdom as across countries from time immemorial traditional healers have been using herbal drugs for management of snake bite. Objective: To evaluate anti-snake venom activities of ethanol and aqueous extracts of Asparagus racernosus (AR) against Indian cobra (Naja naja) venom induced toxicity. Materials and Methods: Anti-snake venom activities of Asparagus racernosus against Indian cobra (Naja naja) venom induced toxicity was studied via in vitro phospholipase A2 induced hemolysis on sheep RBC and Naja naja venom induced anticoagulation, in- vivo neutralization activity against lethality induced by Naja naja venom in rats, Naja naja venom induced edema and effect on bleeding time of venomized rats.