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ABSTRACT
Comparative Study of Nebulized Hypertonic Saline (3%) Epinephrine and Normal Saline in the Management of Children with Acute Bronchiolitis
Dr. Nikhil Sharma
ABSTRACT
BACKGROUND: Nebulized adrenaline is used as preferred treatment in addition to supportive care in bronchiolitis but it causes tachycardia. Nebulized 3% saline and normal saline are also used. Few studies compared these 3 in efficacy and safety. MATERIAL AND METHODS-Observational analytical study including 90 Children divided in 3 groups, aged 2-24 months, presenting with bronchiolitis. Length of hospital stay and treatment failure at 24 hours were the primary outcomes .Clinical scoring system by Uyan et al was used. Group A received Epinephrine, Group B received HS and Group C received NS. Patients enrolled successively in three groups. Scores and heart rate were monitored at 24 hours. Increase in score of 2 or more (from admission score) or heart rate above 200 or 10% increase over baseline, considered as treatment failure.
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