Carole Chibuzo Nweze

ABSTRACT

Many medicinal plants use traditionally have been in use by man without the actual knowledge of their toxic potential. One of such plants used is tobacco plant leave (Nicotiana tabacum), which is chewed in order to relax the smoker. This work is aimed at determining the biochemical effects of aqueous leaves extracts of Tobacco plant (Nicotiana tabacum) in some liver indices in Wistar albino rats. Four groups of animals were studied. The Wistar rats were divided into four groups. Group 1 was treated with normal saline orally, group 2, 3 and 4 were treated with 0.5mL of the extracts, 200 mg/kg, 400 mg/kg and 600 mg/kg respectively.